Despite uncertainty in the KDIGO guidelines, new research has shown that they can accurately identify acute kidney injury in critically ill patients who have a high risk of mortality. Future refinements to AKI definitions will require biomarkers, and robust assessments in prospective studies.
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Jha, V., Kumar, V. Validating the KDIGO definition and staging—one step at a time. Nat Rev Nephrol 10, 550–551 (2014). https://doi.org/10.1038/nrneph.2014.160
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DOI: https://doi.org/10.1038/nrneph.2014.160